Prof. Dr. Peter Krawitz

Our research aims at deepening the understanding of genome biology and advancing personalized medicine. For monogenic disorders we apply next-generation phenotyping technology (NGP) to identify novel disease-causing genes and to improve diagnostics (prioritization of exome data by image analysis, PEDIA study). For complex diseases we approach the puzzle of missing heritability from two different directions: We use NGP to substructure the disease entities. We use polygenic risk modeling and epistasis models to detect gene-gene interactions.